A Close Look at AI Drafting and Documentation at Mayo Clinic – Healthcare AI Pioneers
Jesse chats with Dr. Heather Heaton, Associate Professor of Emergency Medicine, Consultant, and Vice Chair of Clinical Systems Oversight at Mayo Clinic; Dr. Shant Ayanian, Academic Hospitalist and Data Scientist in the Division of Hospital Internal Medicine at Mayo Clinic; and Angie Griffin, Director of Strategy and Innovation for Clinical Systems at Mayo Clinic. Together, they discuss a study evaluating Epic’s LLM-based hospital course drafting tool against human-written summaries across 100 real hospitalizations at Mayo; whether AI performance compared to humans is a win for AI, a damning statement about human baseline quality, or both; design or workflow interventions that can prevent the “rubber stamp” problem of clinicians signing AI-generated documentation without review; which tools in Mayo’s growing AI portfolio get rigorous independent evaluation; Mayo’s governance structure for clinical AI tools; recommendations for health systems that considering Epic’s AI hospital course drafting tool; where AI-assisted clinical documentation could be headed; and much more.
Headline
Researchers at Harvard and Beth Israel Deaconess find OpenAI’s o1 model outperformed two attending internal medicine physicians on real-world emergency department clinical reasoning.
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About Our Guests
Dr. Heather Heaton

Heather A. Heaton, MD, MS, is Associate Professor of Emergency Medicine, a Consultant, and the Vice Chair of Clinical Systems Oversight in the Department of Emergency Medicine at Mayo Clinic in Rochester, Minnesota.. Her research includes AI model generalizability across emergency departments, clinical documentation quality and note bloat, ambient AI scribes, and ML deployment in the live EHR.
Dr. Shant Ayanian

Shant Ayanian, MD, MS, is an academic hospitalist and data scientist in the Division of Hospital Internal Medicine at Mayo Clinic. His research focuses on using advanced analytics and AI to improve clinical care, with deep expertise in ML model development, EHR integration, and machine learning operations.
Angie Griffin

Angie Griffin is Director of Strategy and Innovation for Clinical Systems at Mayo Clinic. With over a decade of experience in managing relationships, designing processes, and implementing software in healthcare organizations across the United States, she is a strategic leader who sits at the intersection of clinical operations and enterprise technology.

