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A Close Look at AI Drafting and Documentation at Mayo Clinic
Jesse chats with Dr. Heather Heaton, Dr. Shant Ayanian, and Angie Griffin about a study evaluating Epic’s LLM-based hospital course drafting tool against human-written summaries across 100 real hospitalizations at Mayo; whether AI performance compared to humans is a win for AI, a damning statement about human baseline quality, or… Listen ⇢
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Overcoming AI Implementation Challenges at the University of Michigan Health System
Jesse chats with Dr. Andrew Wong and Dr. Mike Burns about what led Michigan to report on the underperformance of Epic’s sepsis prediction model, considerations for health systems as they look to set up a structure for AI governance, market diversity and competition in today’s clinical AI sector, the University… Listen ⇢
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Healthcare AI’s ‘Giant Leap’ with Dr. Bob Wachter
Jesse chats with Dr. Bob Wachter about Bob’s new book; why the current healthcare AI boom is different from the many past waves of health tech hype; unintended consequences of electronic health records and lessons from the EHR rollout that could guide AI deployment in healthcare; the balance between AI replacing doctors and assisting them; what’s preventing AI from reliably outperforming human clinicians; how… Listen ⇢
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Expanding AI’s Role in Emergency Triage at Yale
Jesse chats with Dr. Rohit Sangal and Chris Chmura about how they first gained interest in the AI triage area; the role of the Yale Medical School and the Yale New Haven Hospital in an AI triage initiative; metrics, data, and results from what they’ve implemented thus far; overcoming challenges… Listen ⇢
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Operationalizing Clinical AI at Scale at Mount Sinai
Jesse chats with Lisa Stump and Dr. Robbie Freeman about how Mount Sinai Health System thinks about its clinical AI strategy and is implementing scalable programs, how Mount Sinai is using ambient scribing in nursing, using AI to create a program that tracks the risk of pressure ulcers, how Mount… Listen ⇢
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Transforming Care Delivery at Houston Methodist
Jesse chats with Nassib Chamoun and Brenda Campbell about how Houston Methodist is operationalizing AI within its care delivery system, why it needed to rethink how it identifies and manages high-risk patients post-discharge, how predictive models and AI-generated chart summaries actually show up in a clinician’s day-to-day workflow, how AI… Listen ⇢
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Trailer
Healthcare AI Pioneers is a brand-new podcast hosted by Jesse Pines, MD, that aims to demystify the rapid advancements of AI in healthcare. The show focuses on clinician-facing AI, operational AI, and consumer tools. It features insights from leaders who share real-world implementations, outcomes, and challenges without exaggeration. Subscribers can… Listen ⇢
Meet Host Jesse Pines, MD
Jesse M. Pines, MD, MBA, MSCE, is the Chief of Clinical Innovation at US Acute Care Solutions. In this role, Dr. Pines leads efforts in alternative payment models, telemedicine, research, and other innovative programs. He serves as an elected member of the USACS National Clinical Governance Board. He also serves as Director of the USACS Fellowship in Clinical Innovation. Dr. Pines is a Professor of Emergency Medicine at Drexel University and a Clinical Professor of Emergency Medicine at George Washington University (GW). Prior to joining USACS, Dr. Pines held several University leadership and teaching roles at GW and Penn, including serving as the Director of the Center for Healthcare Innovation & Policy Research (CHIPR) at GW and Director of GW’s Center for Health Care Quality (CHCQ). He was also the principal investigator for Urgent Matters, a program that disseminates information on best practices in emergency care.
Dr. Pines earned a bachelor’s in the biological basis of behavior, a master’s degree in clinical epidemiology from the University of Pennsylvania, and a medical degree and MBA from Georgetown University. He completed a residency in emergency medicine at the University of Virginia Health Sciences Center and a fellowship in research at the University of Pennsylvania. He has also completed the Master Teacher Leadership Development Certificate Program at GW School of Education & Human Development.


